… reorganization and disrupts epithelial barrier integrity 100 4.1. … of protein toxins that enter
mammalian cells and covalently modify … Clostridium sordellii lethal toxin kills mice by inducing a …

… , and likely to change these through DNA recombination. … , increasing the permeability of
epithelial and endothelial cells (both … are unable to cross the blood–brain barrier. However, the …

… specifically inhibited by Clostridium sordellii lethal toxin (LT). … to increased vascular
permeability, tissue edema and death … were not mediated by a change in cholesterol levels, we …

… the intestinal barrier without significant alteration of intestinal cells, transits in … intercellular
junctions, morphological changes of intestinal … sordellii (previously Clostridium sordellii) toxins (…

… the toxin-induced elevation of intestinal permeability is accompanied by a histological change
in the intestinal epithelia. … epithelial barrier function is disrupted after treatment with delta-…

… and subsequent disruption of intercellular junctions [35,38]. … membrane receptors, allowing
these modified toxins to attack the … Clostridium sordellii lethal toxin Porcine brain phosphatidyl …

… , producing an increased paracellular permeability in cultured intestinal cells in vitro [Citation…
the exposure of toxin receptors on the host cell surface and/or NanI modifying the host …

… tors have an impact on the permeability of the outer membrane barrier function: (I… toxin
family such as Clostridium sordellii lethal toxin possess a different substrate specificity and modify …

… results in cell death, loss of intercellular junctions, and increase in cell-barrier permeability.
… with abscesses, hepatocellular fatty change, plant toxins, telangiectasia, liver biopsy, and …

… ETX increases intestinal permeability and passes into the … intestinal barrier by transcytosis
without alteration of intestinal … Clostridium difficile and clostridium sordellii large clostridial …